Search on: IMMUNOGLOBULIN ALPHA-CHAINS 
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Descriptor English:   Immunoglobulin alpha-Chains 
Descriptor Spanish:   Cadenas alfa de Inmunoglobulina 
Descriptor Portuguese:   Cadeias alfa de Imunoglobulina 
Synonyms English:   Immunoglobulins, alpha-Chain  
Tree Number:   D12.776.124.486.485.114.619.026.515
D12.776.124.486.485.705.500.350
D12.776.124.790.651.114.619.026.515
D12.776.124.790.651.705.500.350
D12.776.377.715.548.114.619.026.515
D12.776.377.715.548.705.500.350
Definition English:   The class of heavy chains found in IMMUNOGLOBULIN A. They have a molecular weight of approximately 58 kDa and contain about 470 amino acid residues arranged in four domains and an oligosaccharide component bound covalently to their Fc fragment constant region. 
Indexing Annotation English:   gammopathy: coordinate IMMUNOGLOBULIN ALPHA-CHAINS (IM) with PARAPROTEINEMIAS (IM) but consider also HYPERGAMMAGLOBULINEMIA (IM) or ALPHA-CHAIN DISEASE (IM), follow text; DF: IG ALPHA CHAIN
Pharmacological Action:   Immunologic Factors
 
History Note English:   2006 (1976) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis BI biosynthesis
BL blood CF cerebrospinal fluid
CH chemistry CL classification
CT contraindications DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PD pharmacology PH physiology
PO poisoning RE radiation effects
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   30358 
Unique Identifier:   D007137 

Occurrence in VHL:
 

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